See drastic results in just 42 days!
An appetite-decreasing protein injected into the bloodstream of fat monkeys helps the primates quickly lose weight and be less likely to develop diabetes. The protein, called GDF15, has been shown to naturally regulate body weight in most mammals. However this breaks down too quickly in the bloodstream, rendering it useless as an obesity treatment.
So, Murielle Véniant from the pharmaceutical company Amgen and colleagues developed a way for GDF15 to last longer inside the body: they've added an antibody fragment into the protein. When tested and injected into obese monkeys, the primates ate around 40 per cent less! And when given weekly injections, the monkeys lost 10 per cent of their body weight after only six weeks! The primates were also found to be less likely to develop type 2 diabetes as their glucose tolerance improved.
Other obesity treatments approved by the Food and Drug Authority helps one lose an average of seven to 12 per cent of body weight in the span of one year. The gold standard for weight loss, bariatric surgery, helps one lose around 20 to 30 per cent of body weight in just the first year of treatment but has complications, side effects, and is expensive.
According to Véniant, their GDF15 hybrid protein didn't have and recognizable side effects in the primates. But she added that the purpose of the study was to see how effective the hybrid protein is. Further research is required to see how the drug works in people and if it has any complications like nausea.
If these drugs work in humans soon, wouldn't this encourage gluttony as losing weight will be as easy as gaining it? Both blessing and a curse, eh?
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