The technology that can print human skin has finally arrived! A group of experts has successfully produced a 3D-bioprinted human skin that can be transplanted to patients, or be used for lab testing of products.
Scientists from the Universidad Carlos III de Madrid (UC3M), CIEMAT (Center for Energy, Environmental and Technological Research), Hospital General Universitario Gregorio Marañón, and the firm BioDan Group collaborated to make this innovation possible! They have already presented a prototype of the 3D bioprinter.
José Luis Jorcano, author of the study, mentioned in an interview
that this skin “can be transplanted to patients or used in business settings to test chemical products, cosmetics or pharmaceutical products in quantities and with timetables and prices that are compatible with these uses.”
Jorcano is also a professor in UC3M’s department of Bioengineering and Aerospace Engineering and head of the Mixed Unit CIEMAT/UC3M in Biomedical Engineering.
The 3d bioprinter produces a material that mimics real human skin, complete with its natural structure. It has the first external layer of the human skin, the epidermis with its stratum corneum; the second layer, the dermis; as well as the last layer consisting of fibroblasts that produce collagen.
Experts used bioinks for 3d bioprinting. Instead of cartridges and colored inks, injectors with biological components are used.
The system behind this process is patented by CIEMAT and licensed by the BioDan Group. The company uses AI that deposits bioinks on a print bed in an orderly manner to produce the skin.
“Knowing how to mix the biological components, in what conditions to work with them so that the cells don’t deteriorate, and how to correctly deposit the product is critical to the system,” Juan Francisco del Cañizo, researcher at the Hospital General Universitario Gregorio Marañón and Universidad Complutense de Madrid told the UC3M
“We use only human cells and components to produce skin that is bioactive and can generate its own human collagen, thereby avoiding the use of the animal collagen that is found in other methods,” the experts added.
The researchers said that this is only the beginning of their work, as they also plan to print other human tissues.