A breakthrough bioprinting technique is made possible in the recent 3D-printed blood vessels implanted in monkeys. It's only about time that experts can bio-engineer a fully working organ.
Chinese scientists from Sichuan Revotek and the Regenerative Medicine Research Center of West China Hospital at Sichuan University successfully bioprinted blood vessels made from stem cells into the chest of 30 rhesus monkeys.
As scientists all over the world are racing towards biosynthetic organs, the Chinese team made this major breakthrough that will catapult regenerative development in the medical industry.
“It is groundbreaking work that will change the way regenerative medicine will develop,” said Sir Alfred Cuschieri of Dundee University who has met with the Chinese group ahead of the development. Cuschieri who is gearing for a partnership with the team added, “They are well ahead of the west.”
Since the technology uses the actual stem cell material from the subject monkey, the assurance of transplantation rejection is very low.
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The method involved a 3D-printing frame filled with the monkey's autologous adipose mesenchymal stem cells (ADSCs) to print prototype of the blood vessels about 2cm long. The method lessens the invasiveness of the entire process.
What has also become unprecedented is the fact that this technique followed the natural regeneration which allowed the implanted vessels to develop into several new cells naturally along with the original ones.
“The tissues we implanted will have mingled with the original ones and grown into a regular vessel,” said Kang Yujian, one of the Sichuan scientists.
The Sichuan group is planning to stage their next experiment with larger group of monkeys.
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