This Cancer Drug May Give Older Women Fertile Ovarian Eggs! Interesting!

Admin | Published 2016-12-11 09:02

Cancer treatment to women with Hodgkin lymphoma shocks ovarian cells into egg development spurs. Will this help fix age-related fertility problems in women?

Kate Garraway, British TV host, First Response Early Result Pregnancy campaign (frisky.com

Fertility in women comes with a biological deadline. It comes to early for some or comes a bit later for most. The more a woman aged, the more her ovaries slack in producing healthy fertile eggs or hardly at all. If a woman plans to conceive, the healthiest and efficient way to do so is before she hits the age of thirty. "In fact, many infertility clinics won't accept patients if they're older than 39 or 40," claims Parenting website. Also, women who are diagnosed with cancer and are undergoing chemotherapy may have their shot of conceiving blown for life. Exposure to high dose of radiation can damage the some or all eggs or cause a loss of follicles in the ovary which can affect fertility. The effect is just the same with some chemo drugs. But a study published in Oxford Journals by University of Edinburgh in Scotland finds this one common cancer drug to have done the contrary. The effect surprisingly does the opposite.

You're a father again..... after the long drought.

The ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) is one of the cancer drugs used to treat Hodgkin lymphoma. The primary determinant of reproductive age in women is the number ovarian non-growing (primordial, intermediate and primary) follicles (NGFs). The study finds that women treated with ABVD contained a higher density of NGFs per cubic millimetre and increased numbers of multiovular follicles in their ovarian tissue compared to women's who have not received the chemotherapy and to those from healthy women. "To find new eggs being made, in such huge numbers, that was very surprising to see," said Evelyn Telfer, co-author of the study told The Telegraph.

Telfer explained that the chemotherapy may have shocked ovarian stem cells into an overdrive, thus new eggs were formed.

Women are born with 800,000 follicles in their ovaries and that depletes over time. The increased numbers of follicles discovered in this study may contest the long-standing belief between age and fertility. The spur of follicles in these women are found to have not grown to maturity. If the research team can induce functional mature eggs out from the spur, the we can say we have one fertility hopeful waiting to be realized into fruition.  
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